In this small RCT of patients with impaired creatinine clearance (gfr<80) and renal artery stenosis (>50%), they were randomized to medical treatment, with or without renal artery stenting. Follow-up did not show a significant benefit to creatinine clearance (although limited by small sample size), but did demonstrate 4 serious complications in the stenting group (including 2 procedure-related deaths). This study failed to show a benefit of renal artery stenting in this patient population, and did show evidence of harm, indicating medical therapy should be the current standard of care for now (abstract)
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