In this large trial of patients being transported by EMS for seizures, the use of IM midazolam ceased seizures as well as IV lorazepam (73% vs 63% ceased by the time they arrived to the ED, respectively), with no difference in adverse event rates. IM benzodiazepines are as safe and effective as IV in patients with status epilepticus (abstract)
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In this large multicenter trial, patients with minor stroke or TIA were randomized to clopidogrel+ASA or ASA alone; 90-day stroke occurred in 8% vs 12% respectively, and rates of hemorrhage or hemorrhagic stroke were the same (abstract).
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