Invasive candidiasis is hard to diagnose and is associated with high mortality. Researchers prospectively validated a simple “candida score” to distinguish between colonization and infection in non-neutropenic ICU patients. A 5 point score (1 for TPN, 1 for surgery on ICU admission, 1 for candida colonization, and 2 for severe sepsis) predicted the incidence of invasive candidiasis: 2.3% for score <3, 8.5% for score 3, 16.8% for score 4, and 23.6% for score 5. For ICU patients with a score <3, invasive candidiasis is unlikely (abstract).
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